Pro-apoptotic Peptide - (5-FAM) labeled

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Synonyms: 5-FAM-klaklakklaklak-NH2

Functional Activity:

This is the pro-apoptotic peptide composed of D-amino acids, 5-FAM labeled. This alpha-helical amphipathic peptide is toxic to eukaryotic cells if internalized by a suitable targeting mechanism. It disrupts mitochondrial membranes upon receptor-mediated cell internalization and causes programmed cell death.

Technical Data:

M.Wt: 1881.3

Sequence (one-letter code): 5-FAM-klaklakklaklak-NH2

Sequence (three-letter code): 5 - FAM - D - Lys - D - Leu - D - Ala - D - Lys - D - Leu - D - Ala - D - Lys - D - Lys - D - Leu - D - Ala - D - Lys - D - Leu - D - Ala - D - Lys - NH2

Excitation (nm): 494

Emission (nm): 521

Solubility: Soluble in DMSO

Purity: >95% (HPLC)

Shipping Conditions: Room temperature

Storage: Store and desiccate at -20°C and protect from light.

Related Products by Target:

References for Pro-apoptotic Peptide - (5-FAM) labeled :

1. Marks, A. et al. Cancer Res. 65, 2373 (2005);

Certificate of Analysis/MSDS is available upon request

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