Human Pulmonary Aorta Smooth Muscle Cells (HPASMC)
Catalog #:
P0016001Shipping advice:
Use only Express Delivery (overnight) for cell lines. International shipping rate please contact us for details
| Frozen vial | USD600.0 |
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Origin:
Normal, established from pulmonary arteriesSpecies:
Homo sapiensTissue:
LungMorphology:
Smooth muscleProperties:
AdherentMedium:
SMC medium + supplement (please refer to Specification sheet)Subculture:
1:3 using 0.25% trypsin or trypsin/EDTA, 5% CO2; 37 degree CFreezing Medium:
Complete culture medium supplemented with 5% (v/v) DMSOBiosafety Level:
I
Bacteria: Negative
Yeast: Negative
Mycoplasma: Negative
HIV: Negative
Hepatitis B: Negative
Hepatitis C: NegativeSterility:
Pathogens:
References for HPASMC cells:
1. Firth, A. L., Yau, J., White, A., Chiles, P. G., Marsh, J. J., Morris, T. A., and Yuan, J. X. Chronic exposure to fibrin and fibrinogen differentially regulates intracellular Ca2+ in human pulmonary arterial smooth muscle (HPASMC) and endothelial cells. Am J Physiol Lung Cell Mol Physiol, 296: L979-986, 2009.
2. Wang, Y. X., Wang, J., Wang, C., Liu, J., Shi, L. P., Xu, M., and Wang, C. Functional expression of transient receptor potential vanilloid-related channels in chronically hypoxic human pulmonary arterial smooth muscle cells (HPASMC). J Membr Biol, 223: 151-159, 2008.
3. Zhu, Y., Zhang, S., Xie, W., Li, Q., Zhou, Y., and Wang, H. Iptakalim inhibited endothelin-1-induced proliferation of human pulmonary arterial smooth muscle cells (HPASMC) through the activation of K(ATP) channel. Vascul Pharmacol, 48: 92-99, 2008.
4. Goncharova, E. A., Lim, P., Goncharov, D. A., Eszterhas, A., Panettieri, R. A., Jr., and Krymskaya, V. P. Assays for in vitro monitoring of proliferation of human airway smooth muscle (ASM) and human pulmonary arterial vascular smooth muscle (HPASMC) cells. Nat Protoc, 1: 2905-2908, 2006.
5. Hu, H. L., Wang, T., Zhang, Z. X., Zhao, J. P., and Xu, Y. J. [The effect of mitochondrial membrane potential on changes of reactive oxygen species and on proliferation of hypoxic human pulmonary arterial smooth muscle cells (HPASMC)]. Zhonghua Jie He He Hu Xi Za Zhi, 29: 727-730, 2006.
6. Hu, H. L., Zhang, Z. X., Zhao, J. P., Wang, T., and Xu, Y. J. [Effect of opening of mitochondrial ATP-sensitive K+ channel on the distribution of cytochrome C and on proliferation of human pulmonary arterial smooth muscle cells (HPASMC) in hypoxia.]. Sheng Li Xue Bao, 58: 262-268, 2006.
7. Iida, H., Jo, T., Iwasawa, K., Morita, T., Hikiji, H., Takato, T., Toyo-Oka, T., Nagai, R., and Nakajima, T. Molecular and pharmacological characteristics of transient voltage-dependent K+ currents in cultured human pulmonary arterial smooth muscle cells (HPASMC). Br J Pharmacol, 146: 49-59, 2005.
