HCA-7 cells
Catalog #:
C0009003
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| Frozen vial | USD620.0 |
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Disease:
Colonic adenocarcinoma, Dukes' stage B
Established from a colon adenocarcinoma of the adenocarcinoma was moderately differentiated
Homo sapiens
Colon
Epithelial
Adherent
Tumorigenic
Female, 58 yrs of age
AddexBio-formulated DMEM (C0003-01) + 10% FBS
1:2 to 1:10 using 0.25% trypsin or trypsin/EDTA, 5% CO2; 37°C
Complete culture medium supplemented with 5% (v/v) DMSO
I
Bacteria: Negative
Yeast: Negative
Mycoplasma: Negative
HIV: Negative
Hepatitis B: Negative
Hepatitis C: Negative
If use of this culture results in a scientific publication, it should be cited in the publication as: HCA-7 (AddexBio C0009003)
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DNA Profile (STR):
Amelogenin: X;
CSF1PO: 11,14;
D13S317: 9;
D16S539: 10,11;
D5S818: 9,12;
D7S820: 11,12;
THO1: 6, 7;
TPOX: 8,10;
vWA: 14,16
Citation Format:
Related cells by Organ:
References for HCA-7 cells:
1. Bicknell, D. C. and Bodmer, W. F. A mutated HLA-A*0101 allele in the colorectal cell line HCA-7. Tissue Antigens, 66: 231-237, 2005.
2. Cherukuri, D. P., Chen, X. B., Goulet, A. C., Young, R. N., Han, Y., Heimark, R. L., Regan, J. W., Meuillet, E., and Nelson, M. A. The EP4 receptor antagonist, L-161,982, blocks prostaglandin E2-induced signal transduction and cell proliferation in HCA-7 colon cancer cells. Exp Cell Res, 313: 2969-2979, 2007.
3. Fujino, H., Toyomura, K., Chen, X. B., Regan, J. W., and Murayama, T. Prostaglandin E regulates cellular migration via induction of vascular endothelial growth factor receptor-1 in HCA-7 human colon cancer cells. Biochem Pharmacol, 81: 379-387.
4. Orido, T., Fujino, H., Hasegawa, Y., Toyomura, K., Kawashima, T., and Murayama, T. Indomethacin decreases arachidonic acid uptake in HCA-7 human colon cancer cells. J Pharmacol Sci, 108: 389-392, 2008.
5. Reti, A., Barna, G., Pap, E., Adleff, V., V, L. K., Jeney, A., Kralovanszky, J., and Budai, B. Enhancement of 5-fluorouracil efficacy on high COX-2 expressing HCA-7 cells by low dose indomethacin and NS-398 but not on low COX-2 expressing HT-29 cells. Pathol Oncol Res, 15: 335-344, 2009.
6. Tavolari, S., Bonafe, M., Marini, M., Ferreri, C., Bartolini, G., Brighenti, E., Manara, S., Tomasi, V., Laufer, S., and Guarnieri, T. Licofelone, a dual COX/5-LOX inhibitor, induces apoptosis in HCA-7 colon cancer cells through the mitochondrial pathway independently from its ability to affect the arachidonic acid cascade. Carcinogenesis, 29: 371-380, 2008.
