5-FAM-GPHRSTPESRAAV (Presenilin 1 domain)

Catalog #:

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Synonyms: GPHRSTPESRAAV, 5 - FAM labeled

Functional Activity:

The native peptide, GPHRSTPESRAAV (345-357) in human; (221-233) or (351-363) in mouse is a part of the hydrophilic loop domain of presenilin 1 that is selectively recognized by GSK-3β. This sequence is not recognized by p38α, p38β, PKC, or CK II.

Technical Data:

M.Wt: 1722.8

Sequence (one-letter code): 5-FAM-GPHRSTPESRAAV

Sequence (three-letter code): 5 - FAM - Gly - Pro - His - Arg - Ser - Thr - Pro - Glu - Ser - Arg - Ala - Ala - Val - OH

Excitation (nm): 494

Emission (nm): 521

Peptide Category: Protein Phosphorylation Related Peptides

Solubility: Soluble in DMSO

Purity: >95% (HPLC)

Shipping Conditions: Room temperature

Storage: Store and desiccate at -20°C and protect from light.

CAS No.: N/A

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References for 5-FAM-GPHRSTPESRAAV :

1. Hirata, Y. et al. Mol. Biol. Cell 14, 302 (2003);

2. Kirschenbaum, F. et al. J. Biol. Chem. 276, 7366 (2001).

Certificate of Analysis/MSDS is available upon request

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