BAD (103 - 127), human, FAM - labeled (a BCL2 antagonist)
Catalog #:
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ABBFO2013-1mg | USD299.0 |
Synonyms: FAM-NLWAAQRYGRELRRMSDEFVDSFKK
Functional Activity:
This is a BCL2-antagonist of cell death peptide fragment that is fluorescently labeled with FAM, Abs/Em=494/521 nm. Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2 (By similarity). Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.
Technical Data:
M.Wt: 3461.8
Sequence (one-letter code): FAM-NLWAAQRYGRELRRMSDEFVDSFKK
Sequence (three-letter code): FAM - Asn - Leu - Trp - Ala - Ala - Gln - Arg - Tyr - Gly - Arg - Glu - Leu - Arg - Arg - Met - Ser - Asp - Glu - Phe - Val - Asp - Ser - Phe - Lys - Lys - OH
Excitation (nm): 494
Emission (nm): 521
Solubility: Soluble in DMSO
Purity: >95% (HPLC)
Shipping Conditions: Room temperature
Storage: Maintain refrigerated at 2-8°C for up to 6 months. Store and desiccate at -20°C and protect from light.
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References for BAD (103 - 127), human, FAM - labeled :
Certificate of Analysis/MSDS is available upon request
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