In vitro Hepatocyte Toxicity

Cytotoxicity is a critical area of concern for drug candidates. Hepatocyte cytotoxicity is a major cause of drug candidate failure, both pre- and post-market launch. AddexBio will conduct cytotoxicity assays for testing the potential of drug candidate-induced cytotoxicity both in liver cell lines, such as Hep G2 or Hep 3B, or using human or rat hepatocytes. We will use XTT as well as LDH assays.