MDA-MB-231 cells
Catalog #:
C0006002
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| Frozen vial | USD420.0 |
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Disease:
Breast adenocarcinoma
Isolated from pleural effusions of a breast cancer patient
Homo sapiens
Breast, mammary gland
Epithelial
Adherent
Aneuploid female with chromosome counts in the near-triploid range
Female, Caucasian, 51 yrs of age
AddexBio-formulated Leibovitz's L-15 Medium (C0006-01) + 10% FBS
1:2 to 1:4 (80-90%) using 0.25% trypsin or trypsin/EDTA, without CO2 (or use a non-vented flask and keep the lid closed); 37°C
Complete culture medium supplemented with 5% (v/v) DMSO
I
Bacteria: Negative
Yeast: Negative
Mycoplasma: Negative
HIV: Negative
Hepatitis B: Negative
Hepatitis C: Negative
Amelogenin: X,X
CSF1PO:12,13
D13S317:13
D16S539:12
D5S818:12
D7S820:8,9
TH01:7,9.3
TPOX:8,9
vWA:15,19
If use of this culture results in a scientific publication, it should be cited in the publication as: MDA-MB-231 (AddexBio C0006002)
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Protein Expression:
Epidermal growth factor (EGF); transforming growth factor alpha (TGF alpha)
Isoenzymes:
Me-2, 1-2; PGM3, 1; PGM1, 1-2; ES-D, 1; AK-1, 1; GLO-1, 2; G6PD B
DNA Profile (STR):
Citation Format:
Related cells by Organ:
References for MDA-MB-231 cells:
1. Altenburg, J. D. and Siddiqui, R. A. Omega-3 polyunsaturated fatty acids down-modulate CXCR4 expression and function in MDA-MB-231 breast cancer cells. Mol Cancer Res, 7: 1013-1020, 2009.
2. Aroui, S., Brahim, S., De Waard, M., Breard, J., and Kenani, A. Efficient induction of apoptosis by doxorubicin coupled to cell-penetrating peptides compared to unconjugated doxorubicin in the human breast cancer cell line MDA-MB 231. Cancer Lett, 285: 28-38, 2009.
3. Aroui, S., Brahim, S., Hamelin, J., De Waard, M., Breard, J., and Kenani, A. Conjugation of doxorubicin to cell penetrating peptides sensitizes human breast MDA-MB 231 cancer cells to endogenous TRAIL-induced apoptosis. Apoptosis, 14: 1352-1365, 2009.
4. Hunakova, L., Sedlakova, O., Cholujova, D., Gronesova, P., Duraj, J., and Sedlak, J. Modulation of markers associated with aggressive phenotype in MDA-MB-231 breast carcinoma cells by sulforaphane. Neoplasma, 56: 548-556, 2009.
5. Liu, Q., Loo, W. T., Sze, S. C., and Tong, Y. Curcumin inhibits cell proliferation of MDA-MB-231 and BT-483 breast cancer cells mediated by down-regulation of NFkappaB, cyclinD and MMP-1 transcription. Phytomedicine, 16: 916-922, 2009.
6. Nakajima, S., Niizeki, H., Tada, M., Nakagawa, K., Kondo, S., Okada, F., and Kobayashi, M. Trichostatin A with adenovirus-mediated p53 gene transfer synergistically induces apoptosis in breast cancer cell line MDA-MB-231. Oncol Rep, 22: 143-148, 2009.
7. Naviglio, S., Di Gesto, D., Romano, M., Sorrentino, A., Illiano, F., Sorvillo, L., Abbruzzese, A., Marra, M., Caraglia, M., Chiosi, E., Spina, A., and Illiano, G. Leptin enhances growth inhibition by cAMP elevating agents through apoptosis of MDA-MB-231 breast cancer cells. Cancer Biol Ther, 8: 1183-1190, 2009.
8. Phromnoi, K., Yodkeeree, S., Anuchapreeda, S., and Limtrakul, P. Inhibition of MMP-3 activity and invasion of the MDA-MB-231 human invasive breast carcinoma cell line by bioflavonoids. Acta Pharmacol Sin, 30: 1169-1176, 2009.
9. Wang, L., Liu, L. H., Shan, B. E., Zhang, C., Sang, M. X., and Li, J. [Celecoxib promotes apoptosis of breast cancer cell line MDA-MB-231 through down-regulation of the NF-kappaB pathway]. Ai Zheng, 28: 569-574, 2009.
