OE33 (JROECL33) cells
Catalog #:
C0013003
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| Frozen vial | USD520.0 |
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Disease:
Esophageal carcinoma
Established from the adenocarcinoma of the lower oesophagus (Barrett's metaplasia), equivalent to JROECL33
Homo sapiens
Esophagus
Epithelial
Adherent
Express HLA-A, -B and -C antigens (MHC class I) and ICAM-1 constitutively. Expression of HLA-DR (MHC class II) can be induced by treatment with interferon-gamma. The cells express epithelial cytokeratins and are tumourigenic in nude mice
Female, Caucasian, 73 years of age
AddexBio-formulated RPMI-1640 Medium(C0004-01) + 10% FBS
1:3 to 1:5 using 0.25% trypsin or trypsin/EDTA, 5% CO2; 37°C
Complete culture medium supplemented with 5% (v/v) DMSO
Bacteria: Negative
Yeast: Negative
Mycoplasma: Negative
HIV: Negative
Hepatitis B: Negative
Hepatitis C: Negative
Origin:
Species:
Tissue:
Morphology:
Properties:
Cytogenic data:
Patient:
Medium:
Subculture:
Freezing Medium:
Biosafety Level:
I
Sterility:
Pathogens:
Protein Expression:
cytokeratin +, cytokeratin-7 +, cytokeratin-8 +, cytokeratin-17 -, cytokeratin-18 +, cytokeratin-19 +, desmin -, endothel -, EpCAM +, GFAP -, neurofilament -, vimentin -
Related cells by Organ:
References for OE33 cells:
1. Zhang, Q., Zhao, X. H., and Wang, Z. J. Flavones and flavonols exert cytotoxic effects on a human oesophageal adenocarcinoma cell line (OE33) by causing G2/M arrest and inducing apoptosis. Food Chem Toxicol, 46: 2042-2053, 2008.
2. Beales, I. L. and Ogunwobi, O. O. Leptin synergistically enhances the anti-apoptotic and growth-promoting effects of acid in OE33 oesophageal adenocarcinoma cells in culture. Mol Cell Endocrinol, 274: 60-68, 2007.
3. Cheong, E., Ivory, K., Doleman, J., Parker, M. L., Rhodes, M., and Johnson, I. T. Synthetic and naturally occurring COX-2 inhibitors suppress proliferation in a human oesophageal adenocarcinoma cell line (OE33) by inducing apoptosis and cell cycle arrest. Carcinogenesis, 25: 1945-1952, 2004.
